Image describes the two talks upcoming in the April Variant Effect Seminar. Olivia Zhang's talk: KBTBD4 Cancer Hotspot Mutations Drive Neomorphic Degradation of HDAC1/2 Corepressor Complexes. Yuta Yamamoto's talk: Scaled multidimensional assays of variant effect for hypertrophic cardiomyopathy. Sign up via the QR code or at varianteffect.org/seminar-series.

Save the date for April's Variant Effects Seminar, where we will be joined by two more speakers with talks covering cancer and cardiology topics.

#Genomics #CancerBiology #VariantInterpretation #DeepMutationalScanning #FunctionalGenomics #ResearchTalk #StructuralBiology #AtlasOfVariantEffect

Research topics include:
#EvoDevo #DevelopmentalBiology #Genomics #Genetics #Physiology #FunctionalGenomics #SingleCell #ComparativeGenomics #Regeneration #Aging #Neurobiology #DiseaseModels #HostMicrobe #Immunology #StemCells #CellBiology #CRISPR #GeneRegulation #Epigenomics #Metabolism #Evolution

Optimizing #CRISPR for #FunctionalGenomics in patient-derived #Xenograft and primary #AcuteMyeloidLeukemia w/ diverse #PathogenicMutations doi.org/10.1016/j.mo... @junwei_s #AML #TranslationalScience

Explore microbial functionality with #metagenomic analysis. Learn strategies for integrating taxonomic & functional insights to reveal biological mechanisms and advance #microbiome research.

#FunctionalGenomics #Bioinformatics #MicrobialResearch #LifeSciences #Genomics https://tinyurl.com/44c6zvzf

Explore how Novogene's CRISPR/Cas9 services enabled precise gene knockout & functional validation in a Marburg University study. See methods, outcomes & implications in the full case study. #CRISPR #GeneEditing #FunctionalGenomics https://tinyurl.com/24p8fwmh

TECHNOLOGY: @nevillesanjana.bsky.social from New York Genome Center and @nyupress.bsky.social discusses the massively-parallel approaches to understand the human noncoding genome and transcriptome at the 2026 AGBT General Meeting.

#AGBTGM26 #FunctionalGenomics #PrecisionMedicine

The annotated blueprint: integrated functional genomic resources for a model tetraploid wheat Triticum turgidum cv Kronos Triticum turgidum cv Kronos is a tetraploid wheat cultivar that underpins one of the most widely used community platforms for functional genomics. Over the past decade, researchers have generated c. ...

Out in New Phytologist!

The annotated blueprint: integrated functional genomic resources for a model tetraploid wheat cv. Kronos 🌾
chromosome-scale genome, high-conf annotations, manually curated 1000+ NLRs, ~3000 remapped datasets

🔗 doi.org/10.1111/nph....
#Plants #Genomics #FunctionalGenomics

✨ In our latest issue, we're excited to share The Theodor Bücher Award Lecture Review ✍️ by Din Baruch, Maya Schuldiner, and Ofir Klein.
📕 A comprehensive overview of yeast libraries and their role in advancing cell biology
Discover the Review, here ➡️ buff.ly/xtMhKAc
#yeast #functionalgenomics

iPS2-seq is a clone-aware platform for #singlecell loss-of-function screening in #hiPSCs and derivatives including #organoids, here revealing SMAD2 role in cardiac progenitor specification from @berterolab.bsky.social @mendjanlab.bsky.social #functionalgenomics ➡️ link.springer.com/article/10.1...

Our @varianteffect.bsky.social annual reports summarize, celebrate and showcase our collective work.
Read the latest 🔖 zenodo.org/records/1833...
View them all 📖 www.varianteffect.org/annual-repor... #AnnualReport #GlobalAlliance
#FunctionalGenomics #Consortium

Today at 9am Pacific | 12pm Eastern! www.varianteffect.org/seminar-seri...
#CRISPR #FunctionalGenomics #ScienceSeminar

🔬New Perturbation Catalogue update!
With a redesigned interface, richer datasets and powerful analysis workflows, it’s now easier than ever to explore genetic perturbation data. www.ebi.ac.uk/perturbation...
#Bioinformatics #FunctionalGenomics
@training.ebi.embl.org @opentargets.org

We’re happy to share our 2025 Annual Report!
A year of "momentum and connections"!
➡️ zenodo.org/records/1833...
#AnnualReport #GlobalAlliance #FunctionalGenomics #VariantEffect #Community

With 5,565 amiRNAs targeting ~82% of the transportome, mTACT enables spatially resolved genetic screens to uncover hidden regulators of signaling molecule transport.

Published in @plantphys.bsky.social

#PlantPhysiology #Arabidopsis #FunctionalGenomics #Transporters #GeneRegulation #PlantScience

a cat holding a sign that says help ALT: a cat holding a sign that says help

I am looking for free trainings in functional genomics, including proteomics, metagenomics, and microbiome-focused studies.
I’d greatly appreciate any courses, lecture series, or other training resources you could recommend. Thank you in advance!
#FunctionalGenomics #OpenScience #EvoBio

Explore how Novogene's CRISPR/Cas9 services enabled precise gene knockout & functional validation in a Marburg University study. See methods, outcomes & implications in the full case study. #CRISPR #GeneEditing #FunctionalGenomics https://bit.ly/42nNT6n

Happy New Year!

We are looking for a postdoc with computational expertise to join our group. Deadline for application is 13th January.

www.cam.ac.uk/jobs/researc...

#newjob #postdoc #vascularbiology #atherosclerosis #cellplasticitycontrol #functionalgenomics #cellheterogeneity

Move before skincare — better circulation means better absorption.
#CirculationBoost #WinterWarmth #NOS3Support #SkincareTips #FunctionalGenomics

Your winter immunity is shaped by detox, antioxidant, stress, and methylation genes.
#WinterImmunity #GST #SOD2 #GPX #BDNF #Methylation #FunctionalGenomics

Winter skin isn’t “just dry.” It’s your biology signaling stress.
#WinterSkin #FunctionalGenomics #CellularHealth #OxidativeStress #DNACompany

Looking forward to meeting in-person again at #WCPG2026 in Glasgow, Scotland! 🏴󠁧󠁢󠁳󠁣󠁴󠁿 #functionalgenomics #mentalhealth

👩‍🔬👨‍🔬in October, we @fg-pgc.bsky.social had our in-person meeting at #WCPG2025 in Cancun, Mexico ! We loved strategizing about how we can make #functionalgenomics #tools and #datasets in #mentalhealth useful for all, to understand the biology of genetic risk ! 🧬🧠

🌟... #functionalgenomics @fg-pgc.bsky.social travels from Germany to Toronto, Canada, @utoronto.ca where Dr PAVEL POWLOWSKI recently obtained his PhD👨‍🎓and studies #genes #endocannabinoids and human cells in a dish #iPSCs in #bipolardisorder. 🧬🧠

🧠... our next young #functionalgenomics brain is Dr FATIMA MOHAMEDELMUGADAM from @unibonn.bsky.social in Germany🌟 She is interested in how genetic variants in different populations of the world contribute to #autism and #ADHD in kids👨‍👩‍👧‍👧

🌟Today @fg-pgc.bsky.social and @pgcgenetics.bsky.social are in Bengaluru, India, where we love to highlight Dr KALYANI BINDU's work and the dynamic #functionalgenomics scene 🧬🧠
She shows that many of the same biological mechanisms play a role in different #mentalhealth disorders ! One drug for all?

🧬 New VESS talk alert! "Understanding GPCRs with massive mutagenesis" with Taylor Mighell @crg.eu @sangerinstitute.bsky.social @embo.org @cam.ac.uk
Watch the Dec 2 seminar now on YouTube
#VariantEffects #GPCR #FunctionalGenomics
🎥 www.youtube.com/watch?v=lSFt...

🥁🎇✨ ... first up is KIRA HÖFFLER @kirahoeffler.bsky.social from the #UniversityofBergen in Norway and #McLeanHospital in Boston ! So tell us, Kira, what do you do in #functionalgenomics and @pgc_fg ?🤔 Any #funfacts #genetics 🐝❓
🧵3/3

On Friday during ABRCMS, Yiju gave an excellent talk on Functional Annotation of Genetic Variants Linked to Gene Expression & Ancestry. Her unwavering confidence in the face of tough questions was a true testament to her exceptional expertise and poise! 💪#OralPresentation #ABRCMS #functionalgenomics

4/ Access the replay, slides, and resources via the QR code👇 or this link 👉 cytosurge.com/live-seq/cel...

#LiveSeq #SingleCell #SameCell #SingleCellSequencing #SingleCellOmics #Omics #SingleCellBiology #Transcriptomics #FunctionalGenomics #NextGenSequencing #NGS #scRNAseq

Photo: White eyed specimen of Apis mellifera from the study (credit: Izaak Gilchrist)

New #OpenAccess work in #RESInsectMolecBio

Eye can see clearly now: Identifying the locus associated with a white-eye mutation in honey #bees (#Apis mellifera)
doi.org/10.1111/imb.70019

#CommunityScience #FunctionalGenomics
@sassanasgari.bsky.social @gulianusslab.bsky.social @wileyeco.bsky.social