Subsidie van provincie voor sterker en toekomstbestendig centrum Losser
#gemeentelosser #provincieoverijssel #wethouderlahdo #wethouder #cml #centrummanagementlosser #subsidie #ondernemers #biz #bedrijveninvesteringszone #losser #beuningen #delutte #overdinkel #glane #glanebeek #twente
🔬 In our latest issue, we invite you to discover the Editor's Choice article exploring deubiquitination mechanism involved in resistance to tyrosine kinase inhibitors in chronic myeloid leukemia, accompanied by an insightful Commentary.
Discover, here ➡️ buff.ly/jdODi5z
#CML #ubiquitin #TKI
Deep learning analysis of over 1500 #CML marrow slides reveals overlooked cytomorphologic features that strongly predict TKI response. A new Morphoclinical model markedly outperforms current risk scores, supporting more precise frontline therapy selection in CML. 👉https://bit.ly/4rP6imf
I decided to do a DHCPv6 lab. Router "iol-0" is the DHCPv6 server and is supplying IPv6 addresses to 2 Linux PCs. I had to install DHCPCD on the Alpine Linux PC. I also had to modify the NETPLAN .yaml file on the Ubuntu PC to handle DHCPv6.
#cisco #ciscomodelinglabs #cml #IPV6 #DHCPv6
This is a simple DHCP Lab which uses VLANs. Anyone doing the CCNA exam should know this stuff. I have VLAN10 and VLAN20 encapsulated and trunked up to the router. Very simple for those getting into the field.
#cisco #ciscomodelinglabs #cml #DHCP #VLAN #TRUNK
I modified my DHCP lab to show a DHCP Relay Agent (iol-1) forwarding DHCP information to the server (iol-0). . The "ip helper-address 10.0.1.1" command on iol-1 is used to initiate forwarding to the server.
#cisco #ciscomodelinglabs #cml #DHCP
Here's another look at DHCP in action. This time Router "iol-0" is offering addresses to two subnets. The attached packet capture also shows "DORA" - Discover, Offer, Request and Acknowledge in action.
#cisco #ciscomodelinglabs #cml #DHCP
I look forward to presenting at CQF Institute’s Portfolio Management in Quant Finance conference next week.
I will present from 15:10 to 15:45 (GMT) according to the schedule below.
Read more and register here: cqfinstitute.org/events/confe...
#quant #finance #markets #investment #tailrisk #cml
Enliven Therapeutics Shares Encouraging Financial Results and Future Clinical Trial Plans #United_States #CML #Boulder #Enliven_Therapeutics #ELVN-001
My story was published on the @bloodcancerunited.bsky.social website 😊 Next Wednesday, it’s 26 yrs since I heard those fateful words, “You have Leukemia.” I’m still here telling my story 🧡💚
bloodcancerunited.org/about-us/sto...
pages.lls.org/ltn/chi/Metr...
#cml #bmt #ltn #michellessunrisecrew
Single-cell #multiomics profiling of #CML #bonemarrow shows reduced #CD4 naïve cells, expanded #CD8 terminal effectors, reduced TCR diversity, and altered immune signaling, highlighting CD8 TE cells as key drivers and therapeutic targets.
#OpenAccess: doi.org/10.1016/j.ge...
An updated version of the Conditional Maximum Loss (CML) Portfolio Optimization article.
Laura Kristensen and I have recently added some minor clarifications.
Find the latest version of the article and its Python code below.
#quant #quantsky #finance #markets #python #investment #risk #cml
Understanding the Fully General Investment Framework (FGIF):
substack.com/profile/1707...
#quant #quantsky #finance #markets #python #investing #investment #cvar #cml #tailrisk
This newsletter tells a story that I have told many times. Still, I present new perspectives here.
At the end, there is the usual popular posts recap. Make sure to check it out :-)
#quant #quantsky #finance #markets #python #investing #investment #data #risk #cvar #cml
Conditional Maximum Loss (CML) is a game changer for path-dependent tail risk optimization.
This article introduces a new investment risk measure specifically designed for fully general Monte Carlo path simulations.
#quant #quantsky #finance #markets #python #investing #investment #cvar #cml
In this Review authors discuss that atypical #CML has sig. dx challenges, diverse mutations & no standard of care, stressing need for better prognostic tools & confirm that allogeneic transplant remains the sole curative therapy, w/ targeted agents under investigation👉https://bit.ly/3XL9xOM
A new multicenter study led by Dr. Akriti Jain sheds light on how blast phase CML is currently treated in the U.S. and which strategies may offer the best outcomes: binaytara.org/cancernews/a...
#LeukemiaResearch #CML #ASH2025 #Hematology #CancerCare #Binaytara
Aftrap eerste Boerenmarkt Losser 2026
#boerenmarkt #horeca #markt #centrumlosser #cml #losser #beuningen #delutte #overdinkel #glane #lonneker #glanerbrug #gronau
We reflect on a key breakthrough in the treatment of #CML with Dr. Jorge Cortes, who has been involved in the development of #TKIs since the early days.
👉 buff.ly/nqiq2ZY
#CancerTreatments
Enliven Therapeutics Reports Encouraging Progress for ELVN-001 in CML Treatment and Sets 2026 Goals #USA #CML #Boulder #Enliven_Therapeutics #ELVN-001
Single-cell sequencing maps expanded and diverse T-cell subsets in the CML bone marrow microenvironment, giving insight into immune dysregulation.
#CML #SingleCell #TCells #CancerImmunity
www.sciencedirect.com/science/arti...
Just testing out a new screen recorder. May need to lower the resolution a bit. Works well though. Have a look:
👇👇👇
youtu.be/g5RI9vnYwWk
#cisco #ciscomodelinglabs #cml
Sutterella species promote MyD88/Trif-dependent cytotoxic T cell exhaustion, thereby impairing anti-leukemic immunity and accelerating #CML progression @cp-cellreports.bsky.social
www.cell.com/cell-reports...
Why #CML returns after treatment is central to Göran Karlsson’s research @lundstem.bsky.social. Using single-cell genomics, he studies the cancer stem cells behind relapse. During a STIAS fellowship in South Africa, he’s working to make this data globally accessible.
www.stias.ac.za/news/one-cel...
I have been busy tinkering with a VLAN Trunking lab. It is not something I practiced every day when I was working. All VLANs are encapsulated using 802.1q. alpine-0 can ping alpine-3 after passing through the trunk.
#cisco #ciscomodelinglabs #cml #VLAN #TRUNK
Show your support and write to the CML board members to support our community workers!!!
#cml
#union
#columbusohio
actionnetwork.org/letters/tell...
Combining asciminib, a first-in-class BCL::ABL1 inhibitor, with a TKI shows increasing efficacy and tolerability over 3 years in #CML, with some patients able to enter treatment-free remission. Presented at #ASH25.
https://bit.ly/4pV8Le2
#leusm
Wishing everyone safe travels to #ASH25! ✈️
Don’t forget to add our three fantastic oral presentations to your conference agendas — you won’t want to miss them!
👉 Get all the details here: lnkd.in/eXSpRef7
Looking forward to seeing you there! 🔬🌟
#ASH25 #hematology #ASH2025 #Leukemia #AML #CML
Treatment-free relapse is a feasible target for patients with #chronicMyeloidLeukemia living in low- and middle-income countries. Presented at #ESMO25, from @hematologyadvisor.bsky.social.
https://bit.ly/4ppEsMq
#CML #leusm
