Avoiding, Treating & Curing Cancer With the Immune System | Dr. Alex Marson Andrew Huberman on YouTube

🛡️ Your immune system has two completely different operating modes, and understanding both actually changes how you think about your health. The innate immune system is your fast, general-purpose first responder — it reacts immediately to anything foreign.

#ImmuneSystem #TCells

Immunity to a Common Virus Could Help Treat Tumors Injecting viral peptides systemically into mice activated immune cells that then targeted pancreatic tumors, opening avenues to more accessible cancer therapy.

Great new article from @thegeekygoth.bsky.social —

Here's how LJI and @ucsdhealth.bsky.social researchers are using viral peptides to combat pancreatic cancer!

bit.ly/46WA6pg #CancerResearch #Health #Medicine #SanDiego #Oncology #Tcells #PancreaticCancer #Immunotherapy

Scientists have long known that the Epstein–Barr virus (#EBV) is linked to multiple sclerosis (#MS). New UCSF research shows that EBV-reactive CD8+ “killer” #Tcells accumulate in the #CNS of people with MS, revealing how EBV may trigger immune-mediated damage.

www.sciencedaily.com/releases/202...

EDITORS’ CHOICE: Single-cell transcriptomics reveal intrinsic and systemic T cell aging in COVID-19 and HIV - Aging-US Research In this study, titled "Single-cell transcriptomics reveal intrinsic and systemic T cell aging in COVID-19 and HIV" and published in Volume 18 of Aging-US, researchers used single-cell RNA sequencing t...

⭐ #EditorsChoice:
“Single-cell transcriptomics reveal intrinsic and systemic T cell aging in COVID-19 and HIV.”

🔗 Read the Editors’ Choice feature:
aging-us.org/2026/03/edit...

#aging #research #HIV #COVID #Tcells #openaccess #openscience #peerreviewed #journal #publishing #meded

CD200R1 promotes the development of murine γδ17 T cells CD200R1 supports the development of murine IL-17–producing γδ T cells.

New data from Holly Linley, Amy Saunders and colleagues @lydiabeckeriii.bsky.social @manchester.ac.uk shows that "#CD200R1 promotes the development of murine #γδ17 #Tcells"

Tictock: A Single-Cell Clock Measures Immune Aging in Viral Infections - Aging-US Research Aging reshapes the immune system in two fundamental ways: it alters the proportions of different immune cell types circulating in the blood, and it induces molecular changes within each individual cel...

✅ Read our #blog post about the #research paper, titled "Single-cell transcriptomics reveal intrinsic and systemic T cell aging in COVID-19 and HIV."

#Summary ⬇️
aging-us.org/2026/03/tict...

#aging #HIV #COVID #Tcells #oa #openscience #peerreviewed #journal #publishing #meded

#ScientistSpotlight 🧪

This week we’re featuring Toby Whitehead, a DPhil student in the Sharma and Davis Labs at the #MRCWIMM.

@rdm.ox.ac.uk @medsci.ox.ac.uk @ox.ac.uk

#WIMMSpotlight #WIMMCommunity #Immunology #CancerResearch #Immunotherapy #TCells #CheckpointBiology #AcademicSky

The virus nearly everyone has and its possible role in MS | The-14 Nearly everyone carries Epstein-Barr virus, but research suggests it may trigger multiple sclerosis, opening new paths for prevention and treatment.

The virus nearly everyone has and its possible role in MS
#Health #MultipleSclerosis #MS #EpsteinBarrVirus #EBV #Neurology #Immunology #BrainHealth #Autoimmune #Science #PublicHealth #Inflammation #BCells #TCells #Healthcare #DiseasePrevention
the-14.com/the-virus-ne...

#Covid #TCells #HIV #MedSky💉

Cancer treatment: Optimization of CAR T-cell therapy – BioNews Central Researchers improve the efficacy of CAR T-cell therapy in solid tumors by modifying T cells to make them resistant to local inhibition within the tumor microenvironment. ...

Researchers improve the efficacy of #CARTCellTherapy in #SolidTumors by modifying #TCells to make them resistant to local inhibition within the #TumorMicroenvironment.
#CancerTreatment

New Single-Cell Transcriptomic Clock Reveals Intrinsic and Systemic T Cell Aging in COVID-19 and HIV - Aging-US Authors A new research paper was published in Volume 18 of Aging-US on February 8, 2026, titled “Single-cell transcriptomics reveal intrinsic and systemic T cell aging in COVID-19 and HIV.”

📈 #TrendingWithImpact:
This #research paper was #published in Volume 18, titled "Single-cell transcriptomics reveal intrinsic and systemic T cell aging in COVID-19 and HIV."

#PressRelease ⬇️
aging-us.net/2026/02/19/n...

#aging #HIV #COVID #Tcells #oa #journal #publishing #press

How vaccines give our immune systems a home advantage | The-14 How vaccines train our immune system’s front-line and adaptive defenses, building lasting protection and giving the body a crucial home advantage.

How vaccines give our immune systems a home advantage
#Health #Vaccines #Immunity #ImmuneSystem #TCells #Microbiology #Medicine #InfectiousDiseases #Measles #COVID19 #mRNA #Vaccination #PreventiveCare #DiseasePrevention #GlobalHealth
the-14.com/how-vaccines...

Engineered extracellular vesicles reprogram T cells by targeting PD-1 and PHB1 signaling, offering new therapeutic strategies for inflammatory bowel disease.
doi.org/10.1038/s413...
#InflammatoryBowelDisease #TCells #ExtracellularVesicles #PD1 #Immunotherapy

🧠CD38 Shields #CNS Tregs From Post-Inflammatory Stress. The study shows that regulatory #Tcells persist in the CNS after the acute phase and are essential to prevent local relapses.

🔗Read a summary of the study on our website: www.synergy-munich.de/aktuelles/ne...

This Genetic Discovery Could Make T Cells Unstoppable Scientists uncover a new “recipe” that shows how exhausted T cells can be reprogrammed to regain their ability to attack tumors.

This Genetic Discovery Could Make T Cells Unstoppable #Science #Biology #Genetics #GeneTherapy #TCells #CancerResearch

scitechdaily.com/this-genetic-discovery-c...

Laura Ciacchi Laura Ciacchi - Postdoctoral Scientist

🔗 Find out more:
RDM profile: www.rdm.ox.ac.uk/people/laura...

#WIMMSpotlight #WIMMCommunity #Immunology #SkinImmunity #TCells #LipidBiology #UVResearch #MRCWIMM

Spatial proteomic image of a lung tumour depicting the immune niche (blue, pink, purple cells) in which CD14+CD4+ T cells reside within the tumour. Tumour cells are coloured in grey.

Using spatial multi‑omics, WEHI scientists have uncovered an unusual population of CD14⁺CD4⁺ T cells in lung tumours, with higher levels linked to poorer patient outcomes.

New study out in @cp-cellrepmed.bsky.social

👉 www.cell.com/cell-reports...

#Cancer #SpatialOmics #TCells

🔬Dianova Anti-TIGIT (Hu) Clone TG1 is the first monoclonal #antibody detecting #TIGIT in routine #FFPE tissue specimen by #IHC

Validated for the identification of TIGIT positive #Tcells infiltrating human #tumours under pathological conditions

🔗www.stratech.co.uk/p...

CD44 is the central traffic controller for immune system function. 🚦 A new @nature.com article finds that when viruses like cytomegalovirus hijack this system, it can impede efficient priming of naive #TCells and the initiation of antiviral CD8 T cell responses.

Learn more: https://bit.ly/3NX2BfL

We kicked off 2026 with our first #CeMMinar featuring David Masopust (UMN Medical School), who shared insights on CD8 #TCells surveillance, migration & memory. Thanks to David & our hosts CeMM PI Clarissa Campbell & Adjunct PI @andreasbergthaler.bsky.social! 👏
#Immunology

Pleased to share new work from us showing effects of elexacaftor/tezacaftor/ivacaftor (ETI) therapy on the function and quality of the T cell compartment in people with cystic fibrosis, both in the airways and systemically.

@ki.se #cysticfibrosis #Tcells #MAIT
rdcu.be/e06Rw

Spilling the T: #Tcells in #tauopathy mechanisms, disease progression, and therapeutic horizons

Megan E. Bosch & Jason D. Ulrich

link.springer.com/article/10.1...

🔴 Live now: Prof. Dr. Maike Hofmann (University Hospital Freiburg) on “T cell exhaustion and beyond: lessons from chronic viral hepatitis” – part of our translational seminar series.
Join 👉 msteams.link/DGTP
#TCells #Hepatitis #HaDEA #EUHealth @ec.europa.eu

Thanks to the Notorious TRG for the shout out to @theresisters.bsky.social podcast “No Ostriching Here.” as we welcomed @fitterhappieraj.bsky.social
for a chat. His candour and his honesty were appreciated.
#Tcells
#friendsofthepod

Under the agreement, 百时美施贵宝 will pay $50M upfront and near-term, with up to ~$800M in development, regulatory, and commercial milestones, plus tiered royalties. The collaboration centers on Janux Therapeutics tumor-activated T cell engager platform, which aims to address one of the biggest limitations of classic T cell engagers: systemic toxicity. Janux's approach uses a masking strategy that keeps the CD3/CD28-binding portion of the molecule inactive in circulation. The mask is cleaved by tumor-associated proteases, activating the therapy only near the tumor and potentially reducing risks like cytokine release syndrome. If it works as intended, this could meaningfully widen the therapeutic window for T cell engagers in solid tumors. The target antigen hasn't been disclosed, other than being expressed across multiple solid tumor types. Janux Therapeutics will handle preclinical work and IND filing, with BMS taking over clinical development after Phase I. Zooming out, this deal fits neatly into 百时美施贵宝's broader strategy. Over the past year, the company has doubled down on oncology and immune-based platforms, from its $1B+ collaboration with Harbour BioMed to access advanced antibody discovery models, to its $1.5B acquisition of Orbital Therapeutics to expand into RNA-enabled cell therapies. While many large pharmas have pulled back from cell therapy, 百时美施贵宝 appears to be leaning in selectively and with an eye toward differentiated technology. This partnership underscores where the field is heading: not just more immune activation, but smarter, more localized immune engagement. If tumor-activated approaches can deliver efficacy without the usual toxicity tradeoffs, they could unlock a much broader role for T cell engagers in solid tumors. Curious to see how this platform performs once it reaches the clinic.

百时美施贵宝 just struck another notable oncology deal, this time partnering with Janux Therapeutics to advance a next-generation T cell–based therapy designed to be active only in the tumor microenvironment.
#BCIC #Biotech #Tcells

Open Call for 1 PhD Position at Università Vita-Salute San Raffaele in the frame of the MSCA Doctoral Network Multiple sclerosis (MS), is an autoimmune disease of the central nervous system (CNS), characterized by demyelination and neuronal loss, along with immune cell brain infiltration and inflammation.

🔬 We’re hiring again!

Looking for 1 #PhD student to join the #MSCA-DN TRANSCEND network 🧬

Project on unconventional #Tcells in #MultipleSclerosis with research exchanges in
🇩🇰 Klaus Eyer’s lab, Aarhus
🇳🇴 Victor Greiff’s lab, Oslo

⏳ Deadline: Feb 28

👉 euraxess.ec.europa.eu/jobs/403235

A black-and-white picture of an old-fashioned microphone, and on it, the picture is labelled with the brand called the ReSisters and their podcast is called.

@theresisters.bsky.social sat down with Dr. Anthony Leonardi @fitterhappieraj.bsky.social to talk about #TCells & the importance of having legit info to make informed health decisions. #womeninpodcasting #healthinfo
Episodes at:
open.spotify.com/episode/2d8r...
podcasts.apple.com/ca/podcast/n...

2026 Angerer Alm T Cell Summit with T Cell Connect Europe (EFIS-IL).
Great discussions on T cell biology and immunotherapy.
#Immunology #TCells #EFIS #Networking

#Immunology #CancerImmunotherapy #Tcells #CheckpointInhibitors

Fine-tuning BACH2 dosage balances stemness and effector function to enhance antitumor T cell therapy - Nature Immunology One of three back-to-back papers to show dosage of BACH2 can modulate T cell differentiation and function and how we might apply this to enhance chimeric antigen receptor T cell therapies for cancer.

Amazing study from @RoychoudhuriLab highlighting the next-gen genetic manipulation to tweak the right amount of protein expression to enhance T cell function in cancers. Kudos to the authors.
Check it out : www.nature.com/articles/s41...

#tcellexhaustion #tcells