Mid-30’s FM w/progressive conductive hearing loss. Clin dx: otosclerosis
Intraop: stapes fixed, remainder of ossicular chain mobile.
📸: stapes with remodeling, transected above footplate
📸: evolving pseudocyst w/i the articular surface (reactive)
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📸Transverse section through the cricoarytenoid joint (CAJ) of the larynx, a true synovial joint. Arrows delineate joint space
📸 Same, just higher mag
📸 Generally surfaced by fibrocartilage (but may be mixed). Synovium present
📸 Synovial lining
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#EmoryPathology
Squamous cell carcinoma of the edentulous alveolar ridge and palate. Cut surface (ms=maxillary sinus; nc=nasal cavity); corresponding low mag image; endophytic (arrow) with cystic cuniculatum-like growth; additional cystic change in scca.
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Image of the Week!
Submitted by: Rebecca Chernock, M.D.
Directory Profile: www.pathologyoutlines.com/directory/re...
Subspecialty: Head & neck
Diagnosis: CMV in a minor salivary gland
#Pathology #PathologyOutlines #ENTPath #PathSky
Submandibular sialolith is a gross-only specimen for us. However…the interesting surface texture piqued my interest. Intact appearance, sectioned, faxitron (in our lab) and low mag histology with arrows highlighting the textured region.
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Will find SNP tissue (arrows in these two low magnification examples) near fungiform, foliate and/or circumvallate papillae of the tongue.
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More recent paper describes a non-canonical fusion
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Idiopathic gingival papillokeratosis with crypt formation.
Uncommon. Generally located along anterior maxillary gingiva in young people. Asymptomatic plaque(s), usually bilateral and white in color. No known risk of transformation.
PMID: 28089460
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ThC: thyroid cartilage, FC: false cord, TC: true cord, ELE: extralaryngeal extension
Parasagittal section through total laryngectomy specimen resected for advanced stage squamous cell carcinoma. Curious finding in the blue box
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Image of the Week!
Submitted by: Shweta Agarwal, M.D.
Directory Profile: www.pathologyoutlines.com/directory/sh...
Subspecialty: Head & neck
Diagnosis: Follicular adenoma, clear cell type
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✅ Squamous Cell Carcinoma (acantholytic type)
Pseudoglandular spaces due to loss of cohesion between squamous cells
Key: NO true glandular differentiation (i.e., no mucin)
Diffusely p40 positive, Ber-EP4/EpCAM (adenocarcinomas) negative
🔬 rosai.secondslide.com/view/sem1142...
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❌ Adenosquamous Carcinoma
Requires TWO distinct malignant components:
1) SCC
2) adenocarcinoma (true glands, often mucin-producing)
🔬 tumourclassification.iarc.who.int/Viewer/Index...
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❌ Mucoepidermoid Carcinoma (neither SCC or adenocarcinoma)
Admixture of mucous cells, intermediate cells, and epidermoid (squamoid) cells.
Often forms cysts (low grade) and solid areas (high grade)
lmpimg.med.utoronto.ca/LMP70237.htm...
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Here is a closer look at the luminal spaces, what do they contain?
A) squamous cells
B) mucin
C) both
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Tonsilar lesion. Is it #TooFarToDiagnose?
🧐🧐
A) Squamous cell carcinoma
B) Adenocarcinoma
C) Both
D) Neither
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rosai.secondslide.com/view/sem1142...
There are people who say that at the end of the week one loses strength, energy... they lie 😅.
Warthin tumor #CytoPath #ENTPath #FNAFriday
H&E stained section of a papillary neoplasm with bland cells arising within the ear
Higher power view of a papillary neoplasm stained with H&E
A bay horse jumping an oxer in a grass field with a blue sky overhead
Jumping into 2025 with an endolymphatic sac tumor, a VHL-associated neoplasm arising in the posterior petrous bone of the ear #pathsky #eqbsky #neuropath #entpath
Juxtaoral organ of Chievitz that was too good not to share.
Should be (incidentally) found in sections containing muscle/fascia medial to the medial pterygoid muscle, so often seen in larger mandibular or buccal SqCC resections.
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Forgot to tag: #PathSky #Pathology #Frozensection #ENTPath
Frozen day is always a day to celebrate...!