#CircularRNA #ChemoResistance

Circ76691 (1 of 6 cirRNAs⏫in #Oxaliplatin resistance #ColoRectalCancer in vitro, also⏫in vivo (N=11)) acts as a miR-589-3p sponge to relieve FGF9➡️⏬CRC apoptosis

Hi circ76691➡️⏬#DiseaseFreeSurvival (TCGA CRC)

#NoncodingRNARes 2025
www.sciencedirect.com/science/arti...

Circular RNA circHomer1 mediates hippocampal functions via ribonucleoprotein granule transport and dendritic targeting of synaptic RNAs Circular RNA circHomer1 mediates the dendritic targeting of mRNAs to shape dendritic spines and hence neuronal functions.

Circular RNA circHomer1 mediates hippocampal functions via ribonucleoprotein granule transport and dendritic targeting of synaptic RNAs | Science Advances www.science.org/doi/10.1126/...

#circRNAs #circHomer1 #plasticity #neuroscience #RNAgranules #synaptic #mRNA #circularRNA

This review covers advances in #circularRNA biology—from #biogenesis and nuclear export to disease mechanisms—highlighting stability, conservation, #tissuespecificity, and progress in detection and clinical #biomarker translation.

#OpenAccess: doi.org/10.1016/j.ge...

Uncover the roles of circular RNAs in gene regulation and disease with Novogene’s circRNA sequencing services. Gain precise insights into their expression and function.

Learn more: https://bit.ly/3P22IE7

#circRNA #CircularRNA #RNASequencing #Transcriptomics #GeneRegulation #GenomicsInnovation

A non-invasive intranasal #CancerVaccine comprising #CircularRNA encapsulated in #LipidNanoparticles elicits potent anti-tumor T cell responses in preclinical #LungCancer models, providing a novel approach for treating mucosal malignancies.

#STTT #OpenAccess: doi.org/10.1038/s413...

Uncover the roles of circular RNAs in gene regulation and disease with Novogene’s circRNA sequencing services. Gain precise insights into their expression and function.

Learn more: bit.ly/3P22IE7

#circRNA #CircularRNA #RNASequencing #Transcriptomics #GeneRegulation #GenomicsInnovation

#CircularRNA role in #Atherosclerosis

Biogenesis/Modes of Back-splicing
1⃣Lariat/Exon skipping
2⃣Intron pairing

Database
👉CircBase
👉CircInteractome
👉CircAtlas

Functions
👉Transcription/splicing/translation
👉miRNA sponge
👉Peptide-encoding

#CurAtheroRep 2025
link.springer.com/article/10.1...

Uncover the roles of circular RNAs in gene regulation and disease with Novogene’s circRNA sequencing services. Gain precise insights into their expression and function.

Learn more: bit.ly/3P22IE7

#circRNA #CircularRNA #RNASequencing #Transcriptomics #GeneRegulation #GenomicsInnovation

Embark on a hands-on exploration to design and synthesize custom mRNA and #circularRNA #therapeutics. This Summer Camp #workshop will guide you through the essential steps to create high-quality RNA constructs for your research.

Register now: hubs.ly/Q03mhqZX0
#RNATherapeutics #mRNA #Genomics

Uncover the roles of circular RNAs in gene regulation and disease with Novogene’s circRNA sequencing services. Gain precise insights into their expression and function.

Learn more: bit.ly/3P22IE7

#circRNA #CircularRNA #RNASequencing #Transcriptomics #GeneRegulation #GenomicsInnovation

#CircularRNA #Atherosclerosis

Human Aortic plaque vs control intima
15⏫ 13⏬

circLARP1B-encoded 243 aa peptide
⏫PDE4c
⏬cAMP-PKA
⏫#SmoothMuscleCell proliferation migration

Can cAMP be detected via WB (Fig 4B 5A)???😛

#Atherosclerosis 2024
www.sciencedirect.com/science/arti...

#CircularRNA #Atherosclerosis

CircBTBD7-encoded 420 aa peptide ⏬#SmoothMuscleCell proliferation migration
via binding to &⏫ubiquitin-proteasome degradation of SLC3A2

Lentiviral CircBTBD7-420aa⏬plaque size in🐭#Atherosclerosis

#JACCBTS 2025
www.sciencedirect.com/science/arti...

#CircularRNA #SmoothMuscleCell

Circ-Sirt6 (cyclized Sirt6 Ex3/4, ⏬by PDGFBB/arterial injury) & IGF2BP2 (as m6A reader)
⏫m6A modif+stabilize Sirt6 mRNA in SMCs➡️
⏫Contractile markers
⏬#Neointima in injured rat carotid artery

@faseborg.bsky.social 2025
faseb.onlinelibrary.wiley.com/doi/10.1096/...

Exploring RNA modifications in infectious non-coding circular RNAs Viroids, small circular non-coding RNAs, act as infectious pathogens in higher plants, demonstrating high stability despite consisting solely of naked RNA. Their dependence of replication on host m...

#research #RNAmodifications #circularRNA

Exploring RNA modifications in infectious non-coding circular RNAs (Vopalensky, Škríba, Chiumenti, Ďuričeková, Šimonová, Lukšan, Cahova) - RNA Biology: doi.org/10.1080/1547...

@iocbprague.bsky.social @czechacademy.bsky.social

#Obelisk #RNA #rRNA #mRNA #tRNA #DNA #Virus #Bacteria #Molecule #Viroid #RibonucleicAcid #CircularRNA #Ribosomes #Reddit

Reddit thread discussion.

A team of researchers stumbled upon strange entities, or obelisks, living inside human bodies.

r/worldnews 7,500+⬆️ 480📝
www.reddit.com/r/worldnews/...

This January, dive into the fascinating world of Non-Coding RNA Biology in Keystone, CO, USA. Why wait to secure your spot? Register now at hubs.la/Q030C5x70 and be part of this groundbreaking event. #KSNCRNA25 #RNA #noncodingRNA #circularRNA #regulatoryRNA

New forms of life discovered inside human bodies Researchers find obelisks, mysterious RNA molecules in human bacteria that challenge our understanding of viruses and microscopic life.

#Obelisk #RNA #rRNA #mRNA #tRNA #DNA #Virus #Bacteria #Molecule #Viroid #RibonucleicAcid #CircularRNA #Ribosomes

Recently, a team of researchers stumbled upon strange entities, or obelisks, living inside of human bodies that had escaped notice until now.

Abridged (shortened) article thread ⬇️ 6 min

Save USD $200 if you register by December 10th for Non-Coding RNA Biology. Join us in Keystone, CO, USA this January with field leaders such as Judy Lieberman, V. Narry Kim, and many others. keysym.us/KSNCRNA25
#KSNCRNA25 #keystoneconferences #noncodingRNA #ncRNA #lncRNA #circularRNA #regulatoryRNA

Circular logic: understanding RNA’s strangest form yet Circular RNAs are prevalent, mysterious and fascinating, but their study requires great care.

Circular logic: understanding RNA’s strangest form yet. #CircularRNA #Nature #TechnologyFeature
www.nature.com/articles/d41...